MP25-16 MEDICATION SWITCHING AFTER INITIAL PHARMACOTHERAPY FOR OVERACTIVE BLADDER

Lesley H. Curtis is Professor in the Departments of Population Health Sciences and Medicine in the Duke School of Medicine and was inaugural chair of the Department of Population Health Sciences.  A health services researcher by training, Dr. Curtis is an expert in the use of health care and Medicare claims data for health services and clinical outcomes research, and a leader in national data quality efforts. Dr. Curtis has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study. Dr. Curtis currently serves as a senior policy advisor at the Food and Drug Administration supporting the Agency’s evidence generation initiative, and is co-PI of the NIH Pragmatic Trials Collaboratory, an NIH initiative to strengthen the national capacity for large-scale research studies embedded in health care delivery.

Areas of expertise: Health Services Research and Health Policy

• Treatment with a minimally invasive neural modulation system (sacral and posterior tibial nerve) for control of urinary continence
  - Application of botox therapy for urinary urge incontinence
  - Evaluation and treatment for nocturnal voiding
  - Application of nerve stimulation for urinary retention
  - Minimally invasive prolapse surgery for pelvic organ prolapse repairs
  - Treatment for stress urinary incontinence with minimally invasive techniques
  - Evaluation of the urinary microbiome as it relates to recurrent urinary tract infections and lower urinary tract symptoms

Health Disparities, Access to Health Care, Women's Health, Latino Health Care, Chronic Disease Management, Socioeconomic Determinants of Health. Population Health.