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Polymer Remodeling Enabled by Covalent Mechanochemistry

Ramirez, Ashley Lauren Black (2013)

Material failure is a ubiquitous problem, and it is known that materials fail at much lower stresses than the theoretical maximum calculated from the number and strength of the individual bonds along the material ...
Probing Mechanical Activation of Covalent Chemistry in Crosslinked Polymer Gels

Wang, Yifei (2013)

Toughness, the measure of how much energy a material can absorb before rupture, is an important property of materials. It has been demonstrated that the toughness of a single polymer chain of <italic>gem</italic>-diha ...
Property Control of Single Walled Carbon Nanotubes and Their Devices

Yuan, Dongning (2008-12-11)

Controlling the properties of single walled carbon nanotubes (SWNTs) is the major challenge toward their future applications. This dissertation describes several contributions to this chanllenge. This dissertation ...
Pump-Probe Molecular Imaging

Matthews, Thomas (2011)

In this dissertation, we develop pump probe spectroscopy as a method to differentiate different chemical varieties of melanin, a common biopigment, and exploit these differences to improve the accuracy of melanoma ...
Regioselective Asymmetric a,a-Bisalkylation of Ketones via N-Amino Cyclic Carbamate Chiral Auxiliaries: Methodology Development and Application to the Total Synthesis of both (+)- and (-)-Stigmolone and Apratoxin D

Wengryniuk, Sarah Elizabeth (2012)

The α-alkylation of ketones is a transformation of central importance to organic synthesis. Our lab recently introduced the N-amino cyclic carbamate (ACC) chiral auxiliaries for asymmetric ketone α-alkylation. ...
The Search for New/Unknown Signals

Chen, Yuming Morris (2011)

This dissertation focuses on a very special topic in the field of Nuclear Magnetic Resonance (NMR) in solution: Intermolecular Multiple Quantum Coherences, or iMQCs, which can only be created by intermolecular dipolar ...
Stereoselective Syntheses of Tetrahydropyrans: Applications to the Synthesis of (+)-Leucascandrolide A, (+)-Dactylolide and (±)-Diospongin A

Lee, Kiyoun (2012)

Substituted tetrahydropyrans are prevalent in natural products that show interesting biological and pharmacological activities. Therefore, demand for new synthetic approaches for the construction of substituted ...
Structure and Morphology Control in Carbon Nanomaterials for Nanoelectronics and Hydrogen Storage

McNicholas, Thomas Patrick (2009)

Carbon nanomaterials have a wide range of promising and exciting applications. One of the most heavily investigated carbon nanomaterial in recent history has been the carbon nanotube. The intense interest in carbon ...
Studies of Ramoplanin Biosynthesis in Actinoplanes ATCC 33076

Hoertz, Amanda J. (2010)

The natural progression from the introduction of an antibiotic into the market to the emergence of resistant strains demands the constant influx of new drugs to treat infection. Ramoplanin A2, a drug with demonstrated ...
Synthesis and Characterization of Second- Generation Iron Pro-chelators

Perez, Lissette (2010)

Excessive amounts of labile metals such as iron, zinc, and copper have been found in the brains of patients diagnosed with various neurodegenerative diseases, which include Alzheimer's and Parkinson's disease. Iron and ...
Synthesis and Mechanistic Study of Carbon Nanotubes and Tungsten Oxide Nanowires by Chemical Vapor Deposition Methods

Qi, Hang (2007-09-28)

Chemical vapor deposition (CVD) is a versatile method for material preparation. Materials from films to nanostructures can be obtained by tuning the parameters of the CVD method. In the field of one-dimensional nanostructures, ...
Synthesis, Functionalization and Application of Few-Walled Carbon Nanotubes

Hou, Ye (2010)

Few-walled carbon nanotubes (FWNTs) have 2 to 3 layers of sidewalls with diameters ranging from 3 to 8 nm and length around tens of micrometers; they are unique MWNTs with perfect graphitization structure as in single ...
Synthesis, Purification and Application of Few-Walled Carbon Nanotubes and Inorganic Nanowires

Qian, Cheng (2007-05-02)

One-dimension (1D) nanostructures such as wires, rods, belts and tubes have become the focus of intensive researches for investigating structure-property relationships and related scientific and technological applications. ...
Theoretical and Computational Aspects of the Optimized Effective Potential Approach within Density Functional Theory

Heaton-Burgess, Tim (2009)

The computational success of density functional theory relies on the construction of suitable approximations to the exchange-correlation energy functional. Use of functional approximations depending explicitly upon the ...
Theoretical Simulations of Optical Rotation and Raman Optical Activity of Molecules in Solution

Mukhopadhyay, Parag (2008-11-24)

Chiroptical spectroscopic techniques such as optical rotation (OR), electronic circular dichroism (ECD), and Raman optical activity (ROA) provide the means to probe molecular dissymmetry, which is the arrangement of ...
Thermodynamic Investigations of Metalloproteins: Metal as Probe and Protein as Probe

Siburt, Claire Jarvis Parker (2010)

In this dissertation several metalloproteins, both metal transport proteins and the classic metalloprotein hemoglobin, are investigated using a variety of biophysical and electrochemical techniques. In each case, ...
Tip-based Creation and Functionalization of Nanoscale Surface Patterns

Woodson, Michael E (2008-07-29)

Nanostructures are being intensely studied due to unusual material properties and simple scaling concerns in the microelectronics industry. Fabricating useful nano-scale structures and devices, either by arranging ...
Towards the Elucidation of Association in Aqueous Solution: Thermodynamic and Structural Studies of Protein - Ligand Interactions

Schmitt, Allison Anne (2012)

Nearly every aspect of biology is controlled by non-covalent association events, but the diversity of these events is astounding. Association constants can vary over at least a dozen orders of magnitude, and timescales ...
An Umpolung Approach to the α-Functionalization of Ketones and Aldehydes

Hatcher, John (2011)

The α-alkylation of N-sulfonyl hydrazones via in situ-derived azoalkenes provides an umpolung approach to ketone α-alkylation that has considerable potential with regard to catalysis and the direct incorporation ...
Unique Contributions of iDQC MR Contrast to Stimuli-Sensitive Liposomal Chemotherapy and Imaging

Howell, Darya Elizabeth Reza (2012)

Liposomes are excellent chemotherapy drug delivery agents, on the cutting edge of cancer treatment technology. Since liposomes are already used to deploy cancer drugs in patients, imaging capacity would make them ...

Now showing items 61-80 of 80

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