Calcium-Response Factor (CaRF) was first identified as a transcription factor based on its affinity for a neuronal-selective calcium-response element (CaRE1) in the gene encoding Brain-Derived Neurotrophic Factor (BDNF). ...

Alzheimer's disease is a complex and progressive neurodegenerative disease leading to loss of memory, cognitive impairment, and ultimately death. To date, six large-scale genome-wide association studies have been conducted ...

<p>The disease process giving rise to cancer involves the consecutive accumulation of genetic or genomic alterations impacting the normal regulation of cellular functions. In cases of hereditary cancers, this process may ...

<p>Mechanisms of sex chromosome dosage compensation vary widely between different vertebrate species. All eutherians, including humans, other primates, and rodents, undergo random X chromosome inactivation in early female ...

<p>Lichens are symbioses between a fungus and a photosynthesizing partner such as a green alga or a cyanobacterium. Unlike mycorrhizal or rhizobial symbioses, the lichen symbiosis is not well understood either morphologically ...

Background: Genetic analyses of human lice have shown that the current taxonomic classification of head lice ( Pediculus humanus capitis) and body lice ( Pediculus humanus humanus) does not reflect their phylogenetic ...

<p>Coal fired power plants are ubiquitous in the United States and most developed countries around the world, providing affordable electricity to consumers. In the US, approximately six hundred power plants generate 136 ...

<p>Amazonia contains the largest remaining tracts of undisturbed tropical forest on earth, and is thus critical to international nature conservation and carbon sequestration efforts. Amazonian forests are notoriously ...

We formulate a novel approach to infer conditional independence models or Markov structure of a multivariate distribution. Specifically, our objective is to place informative prior distributions over graphs (decomposable ...

<p>This thesis explores a few geometric optimization problems that arise</p><p>in robotics and sensor networks. In particular we present efficient</p><p>algorithms for the hitting-set problem and the budgeted hitting-set ...