Browsing by Duke-affiliated Author "Heitman, Joseph"

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  • Park, Hee-Soo; Chow, Eve W. L.; Fu, Ci; Soderblom, Erik J.; Moseley, M. Arthur; Heitman, Joseph; Cardenas, Maria E. (2016-09)
    Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca2+ levels caused by stress, and transduces signals ...
  • Polvi, EJ; Averette, AF; Lee, SC; Kim, T; Bahn, YS; Veri, AO; Robbins, N; Heitman, Joseph; Cowen, LE (2016-10)
    Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance. Defining circuitry controlling these traits opens new opportunities ...
  • Lee, KT; So, YS; Yang, DH; Jung, KW; Choi, J; Lee, DG; Kwon, H; Jang, J; Wang, LL; Cha, S; Meyers, GL; Jeong, E; Jin, JH; Lee, Y; Hong, J; Bang, S; Ji, JH; Park, G; Byun, HJ; Park, SW; Park, YM; Adedoyin, G; Kim, T; Averette, AF; Choi, JS; Heitman, Joseph; Cheong, E; Lee, YH; Bahn, YS (2016-09-28)
    Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis; however, treatment options remain limited. Here we report the construction of 264 signature-tagged gene-deletion strains for 129 putative ...