Bohn, Laura M.; Lefkowitz, Robert J.; Caron, Marc G.
(Society for Neuroscience, 2002-12)
Morphine induces antinociception by activating μ opioid receptors (μORs) in spinal and supraspinal regions of the CNS. βarrestin-2 (βarr2), a G-protein-coupled receptor-regulating protein, regulates the μOR in vivo. We ...