We have used analytical ultracentrifugation to characterize the binding of the methionine repressor protein. MetJ, to synthetic oligonucleotides containing zero to five specific recognition sites, called metboxes. For all ...

We consider a serial supply chain with one supplier and one retailer. Each obtains some demand forecast information, which may be shared or not. We investigate the members' benefits from sharing information. The forecasts ...

Modern day whole-genome sequencing and the ability to make comparisons across many taxa have significantly advanced the study of sex chromosome evolution. The scuttle fly, Megaselia scalaris, is an appropriate model system ...

In soil-mantled steeplands, soil motions associated with creep, ravel, rain splash, soil slips, tree throw, and rodent activity are patchy and intermittent and involve widely varying travel distances. To describe the ...

<p>In <italic>Saccharomyces cerevisiae</italic>, proper maintenance of haploid cell identity requires the SIR complex to mediate the silenced chromatin found at the cryptic mating-type loci, <italic>HML</italic> and ...

<p>Deciphering the molecular mechanisms driving the phenotypic differences between humans and primates remains a daunting challenge. Mutations found in protein coding DNA alone has not been able to explain these phenotypic ...

Arboreal animals with prehensile hands must balance the complex demands of bone strength, grasping and manipulation. An informative example of this problem is that of the aye-aye (Daubentonia madagascariensis), a rare ...

When modeling the large-scale (> km) evolution of coastline morphology, the influence of natural forces is not the only consideration; ongoing direct human manipulations can substantially drive geomorphic change. In this ...

The natural transfer of DNA from mitochondria to the nucleus generates nuclear copies of mitochondrial DNA (numts) and is an ongoing evolutionary process, as genome sequences attest. In humans, five different numts cause ...

Background: Gene duplication, a major evolutionary path to genomic innovation, can occur at the scale of an entire genome. One such "whole-genome duplication" (WGD) event among the Ascomycota fungi gave rise to genes with ...