<p>This dissertation aims to demonstrate the feasibility of direct infarct visualization using 3D medical ultrasound. The dissertation proceeds by providing the first ever demonstration of fully-sampled 3D ultrasonic speckle ...

<p>Epidural cortical stimulation (ECS) is a developing therapy for many neurological disorders. However, the mechanisms by which ECS has its effects are unknown, and this lack of understanding has limited the development ...

<p>Breast cancer screening is currently performed by mammography, which is limited by overlying anatomy and dense breast tissue. Computer aided detection (CADe) systems can serve as a double reader to improve radiologist ...

<p>Advancements in the biotechnology and pharmaceutical fields have led to the development of an expanding number of applications for certain recombinant proteins of interest. As such, the demand for efficient and cost ...

<p>Diffusion-weighted MRI (DWI) is an essential tool in clinical applications such as detecting ischemic stroke, and in research applications studying neuronal connectivity in the brain. Diffusion-weighted imaging with ...

<p>A clinically viable brain-machine interface (BMI) requires a fully-implanted wireless neural acquisition system to limit the impediments of percutaneous connections. For an implanted system with an appreciable telemetry ...

<p>X-ray mammography is the most widely used breast cancer imaging technique. However, over 400,000 women newly diagnosed each year are misdiagnosed and undergo a biopsy. Current mammography techniques are limited by: (1) ...

<p>This thesis research builds upon prior work that developed separate SPECT and CT (computed mammotomography, or breast CT) devices that were independently capable of imaging an uncompressed breast in 3D space. To further ...

<p>Optical interrogation techniques are particularly well-suited for imaging tissue morphology, biological dynamics, and disease pathogenesis by providing noninvasive access to subcellular-resolution diagnostic information. ...

<p>Optical coherence tomography (OCT) is a non-invasive optical imaging modality that provides micron-scale resolution of tissue micro-structure over depth ranges of several millimeters. This imaging technique has had a ...