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Browsing Electronic Theses and Dissertations by Duke Department

Browsing Electronic Theses and Dissertations by Duke Department "Medical Physics"

Now showing items 21-40 of 66

Evaluation of Centrally Located Sources in Coincidence Timing Calibration for Time-of-Flight PET

Wargo, Richard Ryan (2012)

Coincidence Timing Calibration (CTC) is an essential part of ensuring proper PET scanner function. The purpose of CTC is to account for timing differences in detector modules. The importance and precision in which this ...
Evaluation of Patient Effective Dose of Neurovascular Imaging Protocols of a C-arm Cone-beam CT & Estimation of Current Source Radioactivity of a Cs-137 Irradiator

Wang, Chu (2012)

<bold>Purpose: </bold>(Project 1) The purpose of this study was three-fold: 1) to estimate the organ doses and effective dose (ED) for patients undergoing neurovascular imaging protocols, 2) to study the effect ...
Evaluation of Quantitative Potential of Breast Tomosynthesis Using a Voxelized Anthropomorphic Breast Phantom

Mehtaji, Deep Sunil (2010)

<bold>Purpose:</bold> To assess the quantitative potential of breast tomosynthesis by estimating the percent density of voxelized anthropomorphic breast phantoms. <bold>Methods and Materials:</bold>A Siemens ...
Evaluation of the Three Dimensional Localization Accuracy Using Cone-beam Computed Tomography in Stereotactic Radiosurgery

Tseng, Tzu-Chi (2012)

<bold>Purpose:</bold> Stereotactic Radiosurgery (SRS) indicates a single fraction, large prescription dose, and high dose gradient radiation treatment for intracranial lesions. The stereotactic immobilization and ...
Evaluation of Volumetric Losses During Radiation Therapy Using Image Guidance of Electronic Portal Imaging Device

Senick, Scott Michael (2010)

<bold>Purpose:</bold> Changes in patient volume, due to tumor shrinkage, dehydration, dysphagia and atrophy, could present issues in the accuracy of dosimetry throughout the course of treatment. The aim of this work is ...
Feasibility of Weighted Dual-Energy Subtraction Using Quasi-Monochromatic Beams for a Dedicated Mammotomography System

Polemi, Andrew Michael (2013)

The goal of this research was to investigate the feasibility of using a weighted dual-energy subtraction method in dedicated breast CT using quasi-monochromatic x-ray beams, to better distinguish soft tissues in the ...
Four-Dimensional Imaging of Respiratory Motion in the Radiotherapy Treatment Room Using a Gantry Mounted Flat Panel Imaging Device

Maurer, Jacqueline (2010)

Imaging respiratory induced tumor motion in the radiation therapy treatment room could eliminate the necessity for large motion encompassing margins that result in excessive irradiation of healthy tissues. Currently ...
Higher Order Tensor Diffusion Imaging of Complex White Matter Fiber Tracts

Murphy, Nicole E. (2012)

Resolving multiple fiber orientations within one imaging voxel is critical for accurate quantification of tissue microstructure and faithful reconstruction of the complex neural fiber pathways. It is recognized that the ...
Inter-Instituion Application of Knowledge-Based IMRT Treatment Planning

Good, David (2012)

Intensity Modulated Radiation Therapy (IMRT) has allowed a large degree of healthy tissue sparing while delivering therapeutic dose to tumors. However, the treatment planning process for IMRT is iterative and time ...
Investigating Functional Breast Image Quality and Quantification with a Dedicated SPECT-CT System

Perez, Kristy Lynn (2011)

This work investigates phantom and subject positioning as well as collecting data with a variety of angular sampling and acquisition trajectories. The overall goal of this work has been to utilize the dedicated, breast ...
Investigation of Patient Positioning Accuracy in Lung Stereotactic Body Radiation Therapy

Turner, Kathryn (2013)

Purpose: It has been shown that patients' irregular breathing can cause variation in the delineation of the internal target volume (ITV) and affect the accuracy of four dimensional computed tomography (4DCT) and cone-beam ...
Knowledge-Based IMRT Treatment Planning for Bilateral Head and Neck Cancer

Schmidt, Matthew Charles (2013)

Intensity-modulated radiotherapy (IMRT) remains the standard of care for external beam radiation therapy for head and neck cancers. Planning for IMRT requires a trial-and-error approach that is completely dependent on ...
Knowledge-based IMRT Treatment Planning for Prostate Cancer

Chanyavanich, Vorakarn (2011)

The goal of intensity-modulated radiation therapy (IMRT) treatment plan optimization is to produce a cumulative dose distribution that satisfies both the dose prescription and the normal tissue dose constraints. The ...
Knowledge-Based IMRT Treatment Planning for Prostate Cancer: Experience with 101 cases from Duke Clinic

Dick, Deon (2012)

Intensity-modulated radiotherapy (IMRT) has become an effective tool for cancer treatment with radiation. However, even expert radiation planners still need to spend a substantial amount of time, approximately 4 hours, ...
Knowledge Based Radiation Therapy with Three Dimensional Registration of the Planning Target Volume

Busselberg, Christopher Lorin (2012)

Knowledge based radiation therapy planning was developed as a way to use a knowledge base of clinically approved radiation therapy plans to shorten the amount of time necessary to create a new treatment plan. The method ...
Light scattering and absorption spectroscopy in three dimensions using quantitative low coherence interferometry for biomedical applications

Robles, Francisco Eduardo (2011)

The behavior of light after interacting with a biological medium reveals a wealth of information that may be used to distinguish between normal and disease states. This may be achieved by simply imaging the morphology ...
MOSFET Sensitivity Variation With Integrated Dose History, Application of MOSFET in CT Dosimetry, Physics Characterization of Portal Monitor and Analysis of Portal Monitor Usage for Screening Contaminated People Based on Queueing Theory

Fredrickson, Mats (2011)

<bold>Purpose</bold>: (1) Evaluate use of portal monitor in a radiological emergency, (2) study the variation of MOSFET sensitivity with integrated dose history and (3) assess the accuracy of AAPM 96 formalism for ...
Multi-Slice Imaging Using a Time-Dependent Phase Constraint Through Hadamard Excitation with SENSE Reconstruction (M-PHENSE)

Hoberg, Jacob Ray (2012)

Image acquisition time is one of the most important considerations for magnetic resonance imaging (MRI). This is especially true for dynamic imaging (such as functional MRI or dynamic contrast enhanced MRI) which require ...
The Need for Adaptive Intensity Modulated Radiotherapy Replanning in Head-and-Neck Patients with Anatomical Changes During Treatment

Rhee, Dong Joo (2013)

AbstractPurpose: The aim of this study is to quantify the effectiveness of adaptive radiation therapy (ART) when anatomical changes to the tumor and/or the organs are observed for head and neck patients during ...
Neutron Dosimetry of Mice Using Monoenergetic Neutron Beams

Fallin, Brent Alan (2011)

In 2009 the researchers at Triangle Universities Nuclear Laboratory (TUNL) participated in a series of experiments with the Radiation Countermeasures Center of Research Excellence (RadCCORE). This thesis project is a ...