Browsing Electronic Theses and Dissertations by Subject "GRP94"

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Identification of Essential Functions of GRP94 in Metazoan Growth Control and Epithelial Homeostasis

Maynard, Jason Christopher (2009)

<p>GRP94, the endoplasmic reticulum Hsp90, is a metazoan-restricted chaperone essential for early development in mammals, yet dispensable for mammalian cell viability. These data suggest that GRP94 is required for important ...
Mechanisms of Molecular Chaperone Surface Binding and Endocytosis: Insights into the Molecular Basis for GRP94 Immune Function

Jockheck-Clark, Angela Roberta (2010)

<p>Extracellular GRP94 can elicit both innate and adaptive immune responses by interacting with endocytic and signaling receptors on professional antigen presenting cells (pAPCs). CD91 was the first receptor proposed to ...