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dc.contributor.advisor Yin, Fang-Fang en_US
dc.contributor.advisor O'Daniel, Jennifer en_US
dc.contributor.author Courlas, Lauren D. en_US
dc.date.accessioned 2010-05-13T17:48:37Z
dc.date.available 2012-05-01T04:30:05Z
dc.date.issued 2010 en_US
dc.identifier.uri http://hdl.handle.net/10161/2499
dc.description Thesis en_US
dc.description.abstract <p>Accurate delivery of external beam radiation therapy relies on localization of the treatment target. For this work, the accuracy of an electromagnetic localization system (ELS) was first verified. Next, prostate deformations and rotations occurring throughout therapy were analyzed. Motion studies were also conducted to investigate the use of the ELS during intensity modulated arc therapy (IMAT) for prostate cancer. Lastly, appropriate margins were determined and new plans utilizing smaller margins were tested for two patients who exhibited large transponder displacements. Electromagnetic alignments were accurate to within 1mm as compared to x-ray imaging. All patients fell within the default geometric residual limit (2mm) and most fell within the default rotation limit (10&deg;). The ELS appeared to be suitable for use during IMAT with a 5mm margin. A 3mm margin was tested and was adequate when the main displacements were translational shifts; however, it was not adequate when large rotational displacements occurred.</p> en_US
dc.format.extent 3417592 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.subject Physics, Radiation en_US
dc.subject Health Sciences, Oncology en_US
dc.subject Electromagnetic Localization en_US
dc.subject Prostate Localization en_US
dc.subject Radiation Oncology en_US
dc.subject Tracking Systems en_US
dc.title Clinical Implementation of a Real-Time Electromagnetic Localization System: Accuracy, Motion and Margin Analysis for IMRT and IMAT Treatments en_US
dc.type Thesis en_US
dc.department Medical Physics en_US
duke.embargo.months 24 en_US

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