Browsing Duke Faculty Scholarship by Duke-affiliated Author "McCusker, John Henry"

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Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2 Delta) mutants is influenced by the carbon source and rapamycin

Kingsbury, Joanne; McCusker, John (SOC GENERAL MICROBIOLOGY, 2010)

The isoleucine and valine biosynthetic enzyme acetolactate synthase (1lv2p) is an attractive antifungal drug target, since the isoleucine and valine biosynthetic pathway is not present in mammals, Saccharomyces cerevisiae ...