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Browsing Duke Faculty Scholarship by Duke-affiliated Author

Browsing Duke Faculty Scholarship by Duke-affiliated Author "Haynes, Barton Ford"

Now showing items 1-9 of 9

The characterization of twenty sequenced human genomes

Haynes, Barton (Public Library of Science, 2010)
Contributions of Mamu-A*01 Status and TRIM5 Allele Expression, But Not CCL3L Copy Number Variation, to the Control of SIVmac251 Replication in Indian-Origin Rhesus Monkeys

Haynes, Barton (PUBLIC LIBRARY SCIENCE, 2010)

CCL3 is a ligand for the HIV-1 co-receptor CCR5. There have recently been conflicting reports in the literature concerning whether CCL3-like gene (CCL3L) copy number variation (CNV) is associated with resistance to HIV-1 ...
Contributions of Mamu-A*01 status and TRIM5 allele expression, but not CCL3L copy number variation, to the control of SIVmac251 replication in Indian-origin rhesus monkeys

Haynes, Barton (Public Library of Science, 2010)
Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 Infection

Gasper-Smith, Nancy; Haynes, Barton (PUBLIC LIBRARY SCIENCE, 2010)

The earliest immune responses activated in acute human immunodeficiency virus type 1 infection (AHI) exert a critical influence on subsequent virus spread or containment. During this time frame, components of the innate ...
Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies

Haynes, Barton (Public Library of Science, 2010)
High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men

Hicks, Charles; Haynes, Barton (PUBLIC LIBRARY SCIENCE, 2010)

Elucidating virus-host interactions responsible for HIV-1 transmission is important for advancing HIV-1 prevention strategies. To this end, single genome amplification (SGA) and sequencing of HIV-1 within the context of a ...
Immunization with Cocktail of HIV-Derived Peptides in Montanide ISA-51 Is Immunogenic, but Causes Sterile Abscesses and Unacceptable Reactogenicity

Weinhold, Kent; Ottinger, Janet; Ferarri, Guido; Montefiori, David; Haynes, Barton (PUBLIC LIBRARY SCIENCE, 2010)

Background: A peptide vaccine was produced containing B and T cell epitopes from the V3 and C4 Envelope domains of 4 subtype B HIV-1 isolates (MN, RF, CanO, & Ev91). The peptide mixture was formulated as an emulsion in ...
Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing

Haynes, Barton (PUBLIC LIBRARY SCIENCE, 2010)

We used ultra-deep sequencing to obtain tens of thousands of HIV-1 sequences from regions targeted by CD8+ T lymphocytes from longitudinal samples from three acutely infected subjects, and modeled viral evolution during ...
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

Haynes, Barton (Public Library of Science, 2010)