Browsing Duke Faculty Scholarship by Duke-affiliated Author "Suliman, Hagir B."

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Co-regulation of nuclear respiratory factor-1 by NF kappa B and CREB links LPS-induced inflammation to mitochondrial biogenesis

Suliman, Hagir; Sweeney, Timothy; Withers, Crystal M.; Piantadosi, Claude (COMPANY OF BIOLOGISTS LTD, 2010)

The nuclear respiratory factor-1 (NRF1) gene is activated by lipopolysaccharide (LPS), which might reflect TLR4-mediated mitigation of cellular inflammatory damage via initiation of mitochondrial biogenesis. To test this ...