Browsing Duke Faculty Scholarship by Duke-affiliated Author "Sempowski, Gregory David"

Now showing items 1-2 of 2

The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease

Sempowski, Gregory; Ventevogel, Melissa (AMER SOC CLINICAL INVESTIGATION INC, 2010)

Thymic graft-versus-host disease (tGVHD) can contribute to profound T cell deficiency and repertoire restriction after allogeneic BM transplantation (allo-BMT). However, the cellular mechanisms of tGVHD and interactions ...
Growth Hormone Mitigates against Lethal Irradiation and Enhances Hematologic and Immune Recovery in Mice and Nonhuman Primates

Chen, Benny; Deoliveira, Divino; Spasojevic, Ivan; Sempowski, Gregory; Wang, Xiaojuan; Gesty-Palmer, Diane; Meadows, Sarah K.; Daher, Pamela; Muramoto, Garrett; Chute, Dr John; Chao, Nelson (PUBLIC LIBRARY SCIENCE, 2010)

Medications that can mitigate against radiation injury are limited. In this study, we investigated the ability of recombinant human growth hormone (rhGH) to mitigate against radiation injury in mice and nonhuman primates. ...