Browsing Duke Faculty Scholarship by Author "0289177"

Now showing items 1-2 of 2

Gait and Behavior in an IL-1-Mediated Model of Rat Knee Arthritis and Effects of an IL1 Antagonist

Allen, Kyle D.; Adams, Samuel; Mata, Brian A.; Shamji, Mohammed F.; Gouze, Elvire; Jing, Liufang; Nettles, Dana; Latt, Dr Daniel; Setton, Lori (Journal of Orthopedic Research, 2011)

Objective: Interleukin-1 beta (IL1β) is a pro-inflammatory cytokine that mediates arthritic pathologies. Our objective was to evaluate pain and limb dysfunction resulting from IL1β over-expression in the rat knee and ...
Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells

Gabr, Mostafa A.; Jing, Liufang; Helbling, Antonia R.; Sinclair, S. Michael; Allen, Kyle D.; Shamji, Mohammed F.; Richardson, William; Fitch, Robert; Setton, Lori; Chen, Jun (Wiley Press, 2011-01-01)

Interleukin-17 (IL-17) is a cytokine recently shown to be elevated, along with interferon-γ (IFNγ) and tumor necrosis factor (TNFα), in degenerated and herniated intervertebral disc (IVD) tissues, suggesting a role for ...