Browsing Duke Faculty Scholarship by Author "0296653"

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C. elegans Germline-Deficient Mutants Respond to Pathogen Infection Using Shared and Distinct Mechanisms

TeKippe, Michael; Aballay, Alejandro (PUBLIC LIBRARY SCIENCE, 2010)

Reproduction extracts a cost in resources that organisms are then unable to utilize to deal with a multitude of environmental stressors. In the nematode C. elegans, development of the germline shortens the lifespan of the ...
High-Throughput Isolation and Mapping of C. elegans Mutants Susceptible to Pathogen Infection

Fuhrman, Laura E.; Aballay, Alejandro (PUBLIC LIBRARY SCIENCE, 2008)

We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C. elegans mutants that exhibit an enhanced pathogen accumulation ...