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Browsing Duke Faculty Scholarship by Duke-affiliated Author

Browsing Duke Faculty Scholarship by Duke-affiliated Author "Ginsburg, Geoffrey Steven"

Now showing items 1-3 of 3

Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events / CLINICAL PERSPECTIVE

Shah, Svati Hasmukh; Bain, James Raymond; Muehlbauer, Mike; Stevens, Robert David; Crosslin, David; Haynes, Carol; Dungan, Jennifer; Newby, Kristin; Hauser, Elizabeth Rebecca; Ginsburg, Geoffrey Steven; Newgard, Christopher Bang; Kraus, William Erle (American Heart Association, 2010-04)

Background— Molecular tools may provide insight into cardiovascular risk. We assessed whether metabolites discriminate coronary artery disease (CAD) and predict risk of cardiovascular events. Methods and Results— We ...
Genome-Wide Association Study of Lp-PLA(2) Activity and Mass in the Framingham Heart Study

Suchindran, Sunil; Rivedal, David; Benjamin, Ashlee; Ginsburg, Geoffrey S.; McCarthy, Dr Jeanette (PUBLIC LIBRARY SCIENCE, 2010)

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants ...
Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

Chiba-Falek, Ornit; Nichols, Marshall; Suchindran, Sunil; Ginsburg, Geoffrey S.; McCarthy, Dr Jeanette (BIOMED CENTRAL LTD, 2010)

Background: Several studies have noted that genetic variants of SCARB1, a lipoprotein receptor involved in reverse cholesterol transport, are associated with serum lipid levels in a sex-dependent fashion. However, the ...