Browsing Duke Faculty Scholarship by Author "0378441"

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Histone Modifications within the Human X Centromere Region

Mravinac, Brankica; Sullivan, Lori; Reeves, Jason W.; Yan, Chris; Kopf, Kristen S.; Sullivan, Beth (PUBLIC LIBRARY SCIENCE, 2009)

Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite DNA that are separated from chromosome arms by unordered alpha satellite monomers and other repetitive elements. Complexities in ...
Telomere Disruption Results in Non-Random Formation of De Novo Dicentric Chromosomes Involving Acrocentric Human Chromosomes

Stimpson, Kaitlin M.; Hayden, Karen E.; Sullivan, Beth (PUBLIC LIBRARY SCIENCE, 2010)

Genome rearrangement often produces chromosomes with two centromeres (dicentrics) that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly ...