Browsing Duke Faculty Scholarship by Author "0382675"

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Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies

Li, Ming; Tang, Haili; Greene, Kelli; Gao, Hongmei; Montefiori, David (PUBLIC LIBRARY SCIENCE, 2010)

A steady increase in knowledge of the molecular and antigenic structure of the gp120 and gp41 HIV-1 envelope glycoproteins (Env) is yielding important new insights for vaccine design, but it has been difficult to translate ...
Inhibition of Adaptive Immune Responses Leads to a Fatal Clinical Outcome in SIV-Infected Pigtailed Macaques but Not Vervet African Green Monkeys

Li, Ming; Tang, Haili; Montefiori, David (PUBLIC LIBRARY SCIENCE, 2009)

African green monkeys (AGM) and other natural hosts for simian immunodeficiency virus (SIV) do not develop an AIDS-like disease following SIV infection. To evaluate differences in the role of SIV-specific adaptive immune ...