Walters, Robert William; Shukla, Arun Kumar; Kovacs, Jeffrey J.; Violin, Jonathan David; DeWire, Scott Matthew; Lam, Christopher; Chen, Ruthie; Muehlbauer, Mike; Whalen, Eric; Lefkowitz, Robert J.
(American Society for Clinical Investigation, 2009-05)
Nicotinic acid is one of the most effective agents for both lowering triglycerides and raising HDL. However, the side effect of cutaneous flushing severely limits patient compliance. As nicotinic acid stimulates the GPCR ...