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Browsing Duke Faculty Scholarship by Subject "candida-albicans"

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Evolution of the sex-Related Locus and Genomic Features Shared in Microsporidia and Fungi

Lee, Soo Chan; Dietrich, Fred; Heitman, Joseph (PUBLIC LIBRARY SCIENCE, 2010)

Background: Microsporidia are obligate intracellular, eukaryotic pathogens that infect a wide range of animals from nematodes to humans, and in some cases, protists. The preponderance of evidence as to the origin of the ...
Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi

Heitman, Joseph (SOC GENERAL MICROBIOLOGY, 2010)

Light is a universal signal perceived by organisms, including fungi, in which light regulates common and unique biological processes depending on the species Previous research has established that conserved proteins, ...
Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

O'Meara, Teresa R. (PUBLIC LIBRARY SCIENCE, 2010)

Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within various tissues in order to establish a human infection. We have identified the C. neoformans Rim101 transcription factor, a highly ...
Transcription Factors Mat2 and Znf2 Operate Cellular Circuits Orchestrating Opposite- and Same-Sex Mating in Cryptococcus neoformans

Lin, Xiaorong; Feretzaki, Marianna; Xue, Chaoyang; Heitman, Joseph (PUBLIC LIBRARY SCIENCE, 2010)

Cryptococcus neoformans is a human fungal pathogen that undergoes a dimorphic transition from a unicellular yeast to multicellular hyphae during opposite sex (mating) and unisexual reproduction (same-sex mating). Opposite-and ...