Browsing Duke Faculty Scholarship by Subject "cytochrome-c"

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Computational Design and Elaboration of a de Novo Heterotetrameric alpha-Helical Protein That Selectively Binds an Emissive Abiological (Porphinato)zinc Chromophore

Therien, Michael (AMER CHEMICAL SOC, 2010)

The first example of a computationally de novo designed protein that binds an emissive abiological chromohore is presented, in which a sophisticated level of cofactor discrimination is pre-engineered. This heterotetrameric, ...
Growth Factor erv1-like Modulates Drp1 to Preserve Mitochondrial Dynamics and Function in Mouse Embryonic Stem Cells

Horn, Sarah; Means, Anthony (AMER SOC CELL BIOLOGY, 2010)

The relationship of mitochondrial dynamics and function to pluripotency are rather poorly understood aspects of stem cell biology. Here we show that growth factor erv1-like (Gfer) is involved in preserving mouse embryonic ...