Browsing Duke Scholarly Works by Subject "damage"

Now showing items 1-3 of 3

DNA Adducts of Decarbamoyl Mitomycin C Efficiently Kill Cells without Wild-Type p53 Resulting from Proteasome-Mediated Degradation of Checkpoint Protein 1

Hunter, Senyene; Meye, Joel (AMER CHEMICAL SOC, 2010)

The mitomycin derivative 10-decarbamoyl mitomycin C (DMC) more rapidly activates a p53-independent cell death pathway than mitomycin C (MC). We recently documented that an increased proportion of mitosenel-beta-adduct ...
Separating DNA with Different Topologies by Atomic Force Microscopy in Comparison with Gel Electrophoresis

Jiang, Yong-Hui; Rabbi, Mahir; Marszalek, Piotr (AMER CHEMICAL SOC, 2010)

Atomic force microscopy, which is normally used for DNA imaging to gain qualitative results, can also be used for quantitative DNA research, at a single-molecular level. Here, we evaluate the performance of AFM imaging ...
Vascular structures for volumetric cooling and mechanical strength

Bejan, Adrian (AMER INST PHYSICS, 2010)

When solid material is removed in order to create flow channels in a load carrying structure, the strength of the structure decreases. On the other hand, a structure with channels is lighter and easier to transport as part ...