Browsing Duke Faculty Scholarship by Subject "group"

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Direct Carbon-Carbon Bond Formation via Soft Enolization: A Biomimetic Asymmetric Mannich Reaction of Phenylacetate Thioesters

Kohler, Mark C.; Yost, Julianne M.; Garnsey, Michelle R.; Coltart, Dr Don (AMER CHEMICAL SOC, 2010)

An asymmetric Mannich reaction of phenylacetate thioesters and sulfonylimines using cinchona alkaloid-based amino (thio)urea catalysts is reported that employs proximity-assisted soft enolization. This approach to enolization ...
Growth Factor erv1-like Modulates Drp1 to Preserve Mitochondrial Dynamics and Function in Mouse Embryonic Stem Cells

Horn, Sarah; Means, Anthony (AMER SOC CELL BIOLOGY, 2010)

The relationship of mitochondrial dynamics and function to pluripotency are rather poorly understood aspects of stem cell biology. Here we show that growth factor erv1-like (Gfer) is involved in preserving mouse embryonic ...