Browsing Duke Faculty Scholarship by Subject "murine model"

Now showing items 1-2 of 2

Role of Mast Cells in Inflammatory Bowel Disease and Inflammation-Associated Colorectal Neoplasia in IL-10-Deficient Mice

Chichlowski, Maciej; Westwood, Greg S.; Abraham, Soman; Hale, Laura (PUBLIC LIBRARY SCIENCE, 2010)

Background: Inflammatory bowel disease (IBD) is hypothesized to result from stimulation of immune responses against resident intestinal bacteria within a genetically susceptible host. Mast cells may play a critical role ...
Traumatic Brain Injury Exacerbates Neurodegenerative Pathology: Improvement with an Apolipoprotein E-Based Therapeutic

Laskowitz, Daniel; Song, Pingping; Wang, Haichen; Vitek, Mike; Dawson, Hana N. (MARY ANN LIEBERT INC, 2010)

Cognitive impairment is common following traumatic brain injury (TBI), and neuroinflammatory mechanisms may predispose to the development of neurodegenerative disease. Apolipoprotein E (apoE) polymorphisms modify ...