Eckhart, Andrea Dawn; Duncan, Sandra; Lefkowitz, Robert J.; Koch, Walter J.
(American Heart Association, 2000-01)
G protein–coupled receptor kinases (GRKs) phosphorylate activated G protein-coupled receptors, including α1B-adrenergic receptors (ARs), resulting in desensitization. In vivo analysis of GRK substrate selectivity has been ...