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Browsing Duke Faculty Scholarship by Subject "oncology"

Now showing items 1-7 of 7

Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma

Ilyasova, Dora (BIOMED CENTRAL LTD, 2010)

Background: Malignant glioma is a rare cancer with poor survival. The influence of diet and antioxidant intake on glioma survival is not well understood. The current study examines the association between antioxidant intake ...
Expression signatures of TP53 mutations in serous ovarian cancers

Baba, Tsukasa; Lee, Paula S.; Barnett, Jason C.; Sfakianos, Gregory P.; Secord, Angeles; Murphy, Susan; Berchuck, Andrew (BIOMED CENTRAL LTD, 2010)

Background: Mutations in the TP53 gene are extremely common and occur very early in the progression of serous ovarian cancers. Gene expression patterns that relate to mutational status may provide insight into the etiology ...
Hodgkin lymphoma treatment with ABVD in the US and the EU: neutropenia occurrence and impaired chemotherapy delivery

Culakova, Eva; Lyman, Gary (BIOMED CENTRAL LTD, 2010)

Background: In newly diagnosed patients with Hodgkin lymphoma (HL) the effect of doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD)-related neutropenia on chemotherapy delivery is poorly documented. The aim of this ...
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells

Misra, Uma K.; Pizzo, Salvatore (LANDES BIOSCIENCE, 2010)

We have previously shown that treatment of prostate cancer and melanoma cells expressing GRP78 on their cell surface with antibody directed against the COOH-terminal domain of GRP78 upregulates and activates p53 causing ...
The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design

Jones, Lee; Kraus, William E.; Potti, Anil; Crawford, Jeffrey; Blumenthal, James; Peterson, Bercedis; Douglas, Pamela (BIOMED CENTRAL LTD, 2010)

Background: The Lung Cancer Exercise Training Study (LUNGEVITY) is a randomized trial to investigate the efficacy of different types of exercise training on cardiorespiratory fitness (VO2peak), patient-reported outcomes, ...
MRP3: a molecular target for human glioblastoma multiforme immunotherapy

Kuan, Chien-Tsun; Wakiya, Kenji; Pegram, Charles; Rasheed, Ahmed; Szafranski, Scott; McLendon, Roger; Bigner, Darell (BIOMED CENTRAL LTD, 2010)

Background: Glioblastoma multiforme (GBM) is refractory to conventional therapies. To overcome the problem of heterogeneity, more brain tumor markers are required for prognosis and targeted therapy. We have identified and ...
Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer

Jones, Lee; Douglas, Pamela; Marcom, P. Kelly; Kraus, William E.; Herndon, James II; Inman, Brant; Allen, Jason; Peppercorn, Jeffrey (BIOMED CENTRAL LTD, 2010)

Background: The Exercise Intensity Trial (EXcITe) is a randomized trial to compare the efficacy of supervised moderate-intensity aerobic training to moderate to high-intensity aerobic training, relative to attention control, ...