Browsing Duke Faculty Scholarship by Subject "randomized controlled-trial"

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Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice

Griffin, Timothy M.; Fermor, Beverley; Setton, Lori; Guilak, Farshid (BIOMED CENTRAL LTD, 2010)

Introduction: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ...
Goal-directed or goal-misdirected - how should we interpret the literature?

Roche, Anthony M.; Miller, Dr Timothy (BIOMED CENTRAL LTD, 2010)

Goal-directed therapy (GDT) can be a vague term, meaning different things to different people and, depending on the clinical environment, sometimes even different things to the same person. It can refer to perioperative ...