Browsing Duke Scholarly Works by Subject "tumors"

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Association between DNA Damage Response and Repair Genes and Risk of Invasive Serous Ovarian Cancer

Schildkraut, Joellen; Moorman, Patricia (PUBLIC LIBRARY SCIENCE, 2010)

Background: We analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), ...
Evidence That SOX2 Overexpression Is Oncogenic in the Lung

Lu, Yun; Futtner, Dr Chris; Xu, Dr Xia; Whitworth, Walter; Onaitis, Mark (PUBLIC LIBRARY SCIENCE, 2010)

Background: SOX2 (Sry-box 2) is required to maintain a variety of stem cells, is overexpressed in some solid tumors, and is expressed in epithelial cells of the lung. Methodology/Principal Findings: We show that SOX2 is ...