Pelak, Kimberly; Shianna, Kevin; Ge, Dr Dongliang; Maia, Jessica; Zhu, Dr Mingfu; Smith, Jason P.; Cirulli, Liz; Fellay, Dr Jacques; Dickson, Sam; Gumbs, Curtis; Heinzen, Erin L.; Need, Anna; Ruzzo, Elizabeth K.; Singh, Dr A; Campbell, Christopher; Hong, Linda; Lornsen, Katharina A.; McKenzie, Alexander; Goldstein, David
(PUBLIC LIBRARY SCIENCE, 2010)
We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...