Browsing Duke Faculty Articles by Duke-affiliated Author "Freedman, Neil Jonathan"

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Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation

Freedman, Neil Jonathan; Lefkowitz, Robert J. (American Society for Clinical Investigation, 2004-05)

Antibodies specific for the β1-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually ...
β-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration

Kim, Jihee; Zhang, Lisheng; Peppel, Karsten C.; Wu, Jiao-Hui; Zidar, David; Brian, Leigh; DeWire, Scott Matthew; Exum, Sabrina; Lefkowitz, Robert J.; Freedman, Neil Jonathan (American Heart Association, 2008-07)

Atherosclerosis and arterial injury-induced neointimal hyperplasia involve medial smooth muscle cell (SMC) proliferation and migration into the arterial intima. Because many 7-transmembrane and growth factor receptors ...