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Browsing Duke Faculty Articles by Duke-affiliated Author "Heinzen-Cox, Erin Lynne"

DukeSpace

Browsing Duke Faculty Articles by Duke-affiliated Author "Heinzen-Cox, Erin Lynne"

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  • The Characterization of Twenty Sequenced Human Genomes
    Pelak, Kimberly; Shianna, Kevin; Ge, Dr Dongliang; Maia, Jessica; Zhu, Dr Mingfu; Smith, Jason P.; Cirulli, Liz; Fellay, Dr Jacques; Dickson, Sam; Gumbs, Curtis; Heinzen, Erin L.; Need, Anna; Ruzzo, Elizabeth K.; Singh, Dr A; Campbell, Christopher; Hong, Linda; Lornsen, Katharina A.; McKenzie, Alexander; Goldstein, David (PUBLIC LIBRARY SCIENCE, 2010)
    We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing
    Cirulli, Liz; Singh, Dr A; Shianna, Kevin; Ge, Dr Dongliang; Smith, Jason P.; Maia, Jessica; Heinzen, Erin L.; Goldstein, David (BIOMED CENTRAL LTD, 2010)
    Background: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, ...