Browsing Duke Faculty Articles by Duke-affiliated Author "McCarthy, Jeanette Just"

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Genome-Wide Association Study of Lp-PLA(2) Activity and Mass in the Framingham Heart Study

Suchindran, Sunil; Rivedal, David; Benjamin, Ashlee; Ginsburg, Geoffrey S.; McCarthy, Dr Jeanette (PUBLIC LIBRARY SCIENCE, 2010)

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants ...
Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study

Chiba-Falek, Ornit; Nichols, Marshall; Suchindran, Sunil; Ginsburg, Geoffrey S.; McCarthy, Dr Jeanette (BIOMED CENTRAL LTD, 2010)

Background: Several studies have noted that genetic variants of SCARB1, a lipoprotein receptor involved in reverse cholesterol transport, are associated with serum lipid levels in a sex-dependent fashion. However, the ...