Browsing Duke Faculty Articles by Subject "database"

Now showing items 1-3 of 3

A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins

Furey, Terry (BIOMED CENTRAL LTD, 2010)

Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of genes that are hyper-edited in their ...
Detection of Alternative Splice Variants at the Proteome Level in Aspergillus flavus

Georgianna, D. Ryan (AMER CHEMICAL SOC, 2010)

Identification of proteins from proteolytic peptides or intact proteins plays an essential role in proteomics. Researchers use search engines to match the acquired peptide sequences to the target proteins. However, search ...
Modeling the Evolution of Regulatory Elements by Simultaneous Detection and Alignment with Phylogenetic Pair HMMs

Majoros, William; Ohler, Uwe (PUBLIC LIBRARY SCIENCE, 2010)

The computational detection of regulatory elements in DNA is a difficult but important problem impacting our progress in understanding the complex nature of eukaryotic gene regulation. Attempts to utilize cross-species ...