Browsing Duke Faculty Articles by Subject "growth-factor receptor"

Now showing items 1-3 of 3

Affecting Rhomboid-3 Function Causes a Dilated Heart in Adult Drosophila

Yu, Lin; Wolf, Matthew (PUBLIC LIBRARY SCIENCE, 2010)

Drosophila is a well recognized model of several human diseases, and recent investigations have demonstrated that Drosophila can be used as a model of human heart failure. Previously, we described that optical coherence ...
Detection of Amino-terminal Extracellular Domain of Somatostatin Receptor 2 by Specific Monoclonal Antibodies and Quantification of Receptor Density in Medulloblastoma

Kuan, Chien-Tsun; Wikstrand, Carol J.; McLendon, Roger; Bigner, Darell (MARY ANN LIEBERT INC, 2009)

Somatostatin receptor 2 (SSTR2) is expressed by most medulloblastomas (MEDs). We isolated monoclonal antibodies (MAbs) to the 12-mer (33)QTEPYYDLTSNA(44), which resides in the extracellular domain of the SSTR2 amino terminus, ...
MRP3: a molecular target for human glioblastoma multiforme immunotherapy

Kuan, Chien-Tsun; Wakiya, Kenji; Pegram, Charles; Rasheed, Ahmed; Szafranski, Scott; McLendon, Roger; Bigner, Darell (BIOMED CENTRAL LTD, 2010)

Background: Glioblastoma multiforme (GBM) is refractory to conventional therapies. To overcome the problem of heterogeneity, more brain tumor markers are required for prognosis and targeted therapy. We have identified and ...