Browsing Duke Faculty Articles by Subject "x-chromosome"

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Expression in Aneuploid Drosophila S2 Cells

Powell, Sara K.; MacAlpine, David (PUBLIC LIBRARY SCIENCE, 2010)

Extensive departures from balanced gene dose in aneuploids are highly deleterious. However, we know very little about the relationship between gene copy number and expression in aneuploid cells. We determined copy number ...
Expression, tandem repeat copy number variation and stability of four macrosatellite arrays in the human genome

Alexander, Graham, Jr. (BIOMED CENTRAL LTD, 2010)

Background: Macrosatellites are some of the largest variable number tandem repeats in the human genome, but what role these unusual sequences perform is unknown. Their importance to human health is clearly demonstrated by ...