Browsing Duke Faculty Articles by Subject "zinc-binding"

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Quantification of the Binding Properties of Cu2+ to the Amyloid Beta Peptide: Coordination Spheres for Human and Rat Peptides and Implication on Cu2+-Induced Aggregation

Hong, Lian; Carducci, Tessa M.; Bush, William D.; Simon, John D. (AMER CHEMICAL SOC, 2010)

There is no consensus on the coordinating ligands for Cu2+ by A beta. However, the differences in peptide sequence between human and rat have been hypothesized to alter metal ion binding in a manner that alters Cu2+-induced ...