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dc.contributor.author Abernethy, AP
dc.contributor.author Aziz, NM
dc.contributor.author Basch, E
dc.contributor.author Bull, J
dc.contributor.author Cleeland, CS
dc.contributor.author Currow, DC
dc.contributor.author Fairclough, D
dc.contributor.author Hanson, L
dc.contributor.author Hauser, J
dc.contributor.author Ko, D
dc.contributor.author Lloyd, L
dc.contributor.author Morrison, RS
dc.contributor.author Otis-Green, S
dc.contributor.author Pantilat, S
dc.contributor.author Portenoy, RK
dc.contributor.author Ritchie, C
dc.contributor.author Rocker, G
dc.contributor.author Wheeler, JL
dc.contributor.author Zafar, SY
dc.contributor.author Kutner, JS
dc.coverage.spatial United States
dc.date.accessioned 2011-04-15T16:46:31Z
dc.date.issued 2010-12
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/21105763
dc.identifier.citation J Palliat Med, 2010, 13 (12), pp. 1407 - 1413
dc.identifier.uri http://hdl.handle.net/10161/3239
dc.description.abstract BACKGROUND: Palliative medicine has made rapid progress in establishing its scientific and clinical legitimacy, yet the evidence base to support clinical practice remains deficient in both the quantity and quality of published studies. Historically, the conduct of research in palliative care populations has been impeded by multiple barriers including health care system fragmentation, small number and size of potential sites for recruitment, vulnerability of the population, perceptions of inappropriateness, ethical concerns, and gate-keeping. METHODS: A group of experienced investigators with backgrounds in palliative care research convened to consider developing a research cooperative group as a mechanism for generating high-quality evidence on prioritized, clinically relevant topics in palliative care. RESULTS: The resulting Palliative Care Research Cooperative (PCRC) agreed on a set of core principles: active, interdisciplinary membership; commitment to shared research purposes; heterogeneity of participating sites; development of research capacity in participating sites; standardization of methodologies, such as consenting and data collection/management; agile response to research requests from government, industry, and investigators; focus on translation; education and training of future palliative care researchers; actionable results that can inform clinical practice and policy. Consensus was achieved on a first collaborative study, a randomized clinical trial of statin discontinuation versus continuation in patients with a prognosis of less than 6 months who are taking statins for primary or secondary prevention. This article describes the formation of the PCRC, highlighting processes and decisions taken to optimize the cooperative group's success.
dc.format.extent 1407 - 1413
dc.language ENG
dc.language.iso en_US en_US
dc.relation.ispartof J Palliat Med
dc.relation.isversionof 10.1089/jpm.2010.0261
dc.subject Cooperative Behavior
dc.subject Evidence-Based Medicine
dc.subject Health Services Research
dc.subject Humans
dc.subject Palliative Care
dc.title A strategy to advance the evidence base in palliative medicine: formation of a palliative care research cooperative group.
dc.type Journal Article
dc.description.version Version of Record en_US
duke.date.pubdate 2010-12-0 en_US
duke.description.endpage 1413 en_US
duke.description.issue 12 en_US
duke.description.startpage 1407 en_US
duke.description.volume 13 en_US
dc.relation.journal Journal of palliative medicine en_US
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/21105763
pubs.issue 12
pubs.organisational-group /Duke
pubs.organisational-group /Duke/Institutes and Provost's Academic Units
pubs.organisational-group /Duke/Institutes and Provost's Academic Units/University Institutes and Centers
pubs.organisational-group /Duke/Institutes and Provost's Academic Units/University Institutes and Centers/Global Health Institute
pubs.organisational-group /Duke/Sanford School of Public Policy
pubs.organisational-group /Duke/Sanford School of Public Policy/Sanford School of Public Policy - Secondary Group
pubs.organisational-group /Duke/School of Medicine
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Medicine
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Medicine/Medicine, Medical Oncology
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers/Duke Cancer Institute
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers/Duke Clinical Research Institute
pubs.organisational-group /Duke/School of Nursing
pubs.organisational-group /Duke/School of Nursing/School of Nursing - Secondary Group
pubs.publication-status Published
pubs.volume 13
dc.identifier.eissn 1557-7740

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