Browsing Duke Dissertations by Subject "2-phenylcyclopropylamine"

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Examination of the Role of Lysine Specific Demethylase 1 (LSD1) and Associated Proteins in Breast Cancer Proliferation using 2-Phenylcyclopropylamine Inhibitors

Pollock, Julie Ann (2011)

<p>Lysine specific demethylase 1 (LSD1) is a FAD-dependent amine oxidase enzyme responsible for removing methyl groups from the side chain nitrogen of lysine within histones in order to regulate gene transcription. By its ...