Browsing Duke Dissertations by Author "Jockheck-Clark, Angela Roberta"

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Mechanisms of Molecular Chaperone Surface Binding and Endocytosis: Insights into the Molecular Basis for GRP94 Immune Function

Jockheck-Clark, Angela Roberta (2010)

<p>Extracellular GRP94 can elicit both innate and adaptive immune responses by interacting with endocytic and signaling receptors on professional antigen presenting cells (pAPCs). CD91 was the first receptor proposed to ...