Browsing Duke Dissertations by Subject "Rac"

Now showing items 1-3 of 3

Abl Tyrosine Kinases Mediate Intercellular Adhesion

Zandy, Nicole Lynn (2008-04-24)

<p>Adherens junctions are calcium-dependent cell-cell contacts formed during epithelial morphogenesis that link neighboring cells via cadherin receptors. Coordinated regulation of the actin cytoskeleton by the Rho GTPases ...
Identification of a Novel Formin-GAP Complex and Its Role in Macrophage Migration and Phagocytosis

Mason, Frank Marshall (2011)

<p>Essential and diverse biological processes such as cell division, morphogenesis and migration are regulated by a family of molecular switches called Rho GTPases. These proteins cycle between active, GTP-bound states and ...
Ras1-mediated Morphogenesis in the Human Fungal Pathogen Cryptococcus Neoformans

Ballou, Elizabeth Ripley (2012)

<p><italic>Cryptococcus neoformans</italic> pathogenesis results from the proliferation of yeast-phase fungal cells within the human host. The Ras1 signal transduction cascade is a major regulator of <italic>C. neoformans</italic> ...