Browsing Duke Dissertations by Subject "a"

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Alteration of Golgi Apparatus Ion Homeostasis in Cellular and Mouse Models of Angelman Syndrome

Condon, Kathryn Helen (2009)

<p>Ube3a is a HECT domain E3 ubiquitin ligase originally recognized for its role in degrading p53 in the presence of the human papilloma virus protein E6. Loss of maternal Ube3a expression causes Angelman syndrome, a ...