Browsing Duke Dissertations by Subject "p53"

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  • Mason, Emily Ferguson (2011)
    <p>Healthy cells require input from growth factor signaling pathways to maintain cell metabolism and survival. Growth factor deprivation induces a loss of glucose metabolism that contributes to cell death in this context, ...
  • Lee, Chang-Lung (2012)
    <p>Radiation therapy can cause acute toxicity and long-term side effects in normal tissues. Because part of the acute toxicity of radiation is due to p53-mediated apoptosis, blocking p53 during irradiation can protect some ...
  • Huang, Nai-Jia (2013)
    <p>Within individual cells, the opposing processes of proliferation and apoptosis are precisely regulated. When this regulatory balance is interrupted, cells may become abnormal or even transformed. Understanding how to ...