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dc.contributor.author Piletic, IR
dc.contributor.author Matthews, TE
dc.contributor.author Warren, WS
dc.coverage.spatial United States
dc.date.accessioned 2011-06-21T17:26:40Z
dc.date.issued 2010-11-04
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/20882951
dc.identifier.citation J Phys Chem A, 2010, 114 (43), pp. 11483 - 11491
dc.identifier.uri http://hdl.handle.net/10161/4073
dc.description.abstract Ultraviolet-visible spectroscopy readily discerns the two types of melanin pigments (eumelanin and pheomelanin), although fundamental details regarding the optical properties and pigment heterogeneity are more difficult to disentangle via analysis of the broad featureless absorption spectrum alone. We employed nonlinear transient absorption spectroscopy to study different melanin pigments at near-infrared wavelengths. Excited-state absorption, ground-state depletion, and stimulated emission signal contributions were distinguished for natural and synthetic eumelanins and pheomelanins. A starker contrast among the pigments is observed in the nonlinear excitation regime because they all exhibit distinct transient absorptive amplitudes, phase shifts, and nonexponential population dynamics spanning the femtosecond-nanosecond range. In this manner, different pigments within the pheomelanin subclass were distinguished in synthetic and human hair samples. These results highlight the potential of nonlinear spectroscopies to deliver an in situ analysis of natural melanins in tissue that are otherwise difficult to extract and purify.
dc.format.extent 11483 - 11491
dc.language ENG
dc.language.iso en_US en_US
dc.relation.ispartof J Phys Chem A
dc.relation.isversionof 10.1021/jp103608d
dc.subject Animals
dc.subject Hair
dc.subject Humans
dc.subject Melanins
dc.subject Quantum Theory
dc.subject Sepia
dc.subject Spectrophotometry, Ultraviolet
dc.title Probing near-infrared photorelaxation pathways in eumelanins and pheomelanins.
dc.title.alternative en_US
dc.type Journal Article
dc.description.version Version of Record en_US
duke.date.pubdate 2010-11-4 en_US
duke.description.endpage 11491 en_US
duke.description.issue 43 en_US
duke.description.startpage 11483 en_US
duke.description.volume 114 en_US
dc.relation.journal Journal of Physical Chemistry a en_US
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/20882951
pubs.issue 43
pubs.organisational-group /Duke
pubs.organisational-group /Duke/School of Medicine
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers
pubs.organisational-group /Duke/School of Medicine/Institutes and Centers/Duke Cancer Institute
pubs.organisational-group /Duke/Trinity College of Arts & Sciences
pubs.organisational-group /Duke/Trinity College of Arts & Sciences/Chemistry
pubs.organisational-group /Duke/Trinity College of Arts & Sciences/Physics
pubs.publication-status Published
pubs.volume 114
dc.identifier.eissn 1520-5215

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