Burkholdines 1097 and 1229, Potent Antifungal Peptides from Burkholderia ambifaria 2.2N

doi:doi:10.1021/ol9029269

dc.contributor.author	Dubay, George	en_US
dc.date.accessioned	2011-06-21T17:27:11Z
dc.date.available	2011-06-21T17:27:11Z
dc.date.issued	2010	en_US
dc.identifier.citation	Tawfik,Kamilia A.;Jeffs,Peter;Bray,Brian;Dubay,George;Falkinham,Joseph O.,,III;Mesbah,Mostafa;Youssef,Diaa;Khalifa,Sherief;Schmidt,Eric W.. 2010. Burkholdines 1097 and 1229, Potent Antifungal Peptides from Burkholderia ambifaria 2.2N. Organic letters 12(4): 664-666.	en_US
dc.identifier.issn	1523-7060	en_US
dc.identifier.uri	http://hdl.handle.net/10161/4111
dc.description.abstract	Potent antifungal cyclic lipopeptides, burkholdines (Bk), were isolated from a culture of Burkholderia ambifaria 2.2N. Bk-1229 (1) and Bk-1097 (2) are octapeptides comprised of nonproteinogenic amino acids, including beta-hydroxytyrosine, beta-hydroxyasparagine, and a new fatty acyl amino acid. 1 and 2 are fungicidal against a panel of fungi with potencies 2-60-fold better than amphotericin B control.	en_US
dc.language.iso	en_US	en_US
dc.publisher	AMER CHEMICAL SOC	en_US
dc.relation.isversionof	doi:10.1021/ol9029269	en_US
dc.subject	amino-acids	en_US
dc.subject	identification	en_US
dc.subject	cepacia	en_US
dc.subject	complex	en_US
dc.subject	strain	en_US
dc.subject	chemistry, organic	en_US
dc.title	Burkholdines 1097 and 1229, Potent Antifungal Peptides from Burkholderia ambifaria 2.2N	en_US
dc.title.alternative		en_US
dc.description.version	Version of Record	en_US
duke.date.pubdate	2010-2-19	en_US
duke.description.endpage	666	en_US
duke.description.issue	4	en_US
duke.description.startpage	664	en_US
duke.description.volume	12	en_US
dc.relation.journal	Organic letters	en_US