Platinum(II)-catalyzed intermolecular hydroamination of monosubstituted allenes with secondary alkylamines

Abstract

A 1 : 1 mixture of (dppf)PtCl2 and AgOTf (5 mol%) catalyzed the intermolecular hydroamination of monosubstituted allenes with secondary alkylamines at 80 degrees C to form allylic amines in good yield with selective formation of the E-diastereomer.