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dc.contributor.author LeCheminant, JD
dc.contributor.author Smith, BK
dc.contributor.author Westman, EC
dc.contributor.author Vernon, MC
dc.contributor.author Donnelly, JE
dc.coverage.spatial England
dc.date.accessioned 2011-06-21T17:29:39Z
dc.date.issued 2010-06-01
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/20515484
dc.identifier 1476-511X-9-54
dc.identifier.citation Lipids Health Dis, 2010, 9 pp. 54 - ?
dc.identifier.uri http://hdl.handle.net/10161/4368
dc.description.abstract OBJECTIVES: This study compared LDL, HDL, and VLDL subclasses in overweight or obese adults consuming either a reduced carbohydrate (RC) or reduced fat (RF) weight maintenance diet for 9 months following significant weight loss. METHODS: Thirty-five (21 RC; 14 RF) overweight or obese middle-aged adults completed a 1-year weight management clinic. Participants met weekly for the first six months and bi-weekly thereafter. Meetings included instruction for diet, physical activity, and behavior change related to weight management. Additionally, participants followed a liquid very low-energy diet of approximately 2092 kJ per day for the first three months of the study. Subsequently, participants followed a dietary plan for nine months that targeted a reduced percentage of carbohydrate (approximately 20%) or fat (approximately 30%) intake and an energy intake level calculated to maintain weight loss. Lipid subclasses using NMR spectroscopy were analyzed prior to weight loss and at multiple intervals during weight maintenance. RESULTS: Body weight change was not significantly different within or between groups during weight maintenance (p>0.05). The RC group showed significant increases in mean LDL size, large LDL, total HDL, large and small HDL, mean VLDL size, and large VLDL during weight maintenance while the RF group showed increases in total HDL, large and small HDL, total VLDL, and large, medium, and small VLDL (p<0.05). Group*time interactions were significant for large and medium VLDL (p>0.05). CONCLUSION: Some individual lipid subclasses improved in both dietary groups. Large and medium VLDL subclasses increased to a greater extent across weight maintenance in the RF group.
dc.format.extent 54 - ?
dc.language eng
dc.language.iso en_US en_US
dc.relation.ispartof Lipids Health Dis
dc.relation.isversionof 10.1186/1476-511X-9-54
dc.subject Diet, Reducing
dc.subject Dietary Carbohydrates
dc.subject Dietary Fats
dc.subject Humans
dc.subject Lipoproteins
dc.subject Lipoproteins, HDL
dc.subject Lipoproteins, LDL
dc.subject Lipoproteins, VLDL
dc.subject Middle Aged
dc.subject Obesity
dc.subject Overweight
dc.subject Weight Loss
dc.title Comparison of a reduced carbohydrate and reduced fat diet for LDL, HDL, and VLDL subclasses during 9-months of weight maintenance subsequent to weight loss.
dc.title.alternative en_US
dc.type Journal Article
dc.description.version Version of Record en_US
duke.date.pubdate 2010-6-1 en_US
duke.description.endpage 54 en_US
duke.description.issue en_US
duke.description.startpage 54 en_US
duke.description.volume 9 en_US
dc.relation.journal Lipids in Health and Disease en_US
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/20515484
pubs.organisational-group /Duke
pubs.organisational-group /Duke/School of Medicine
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Medicine
pubs.organisational-group /Duke/School of Medicine/Clinical Science Departments/Medicine/Medicine, General Internal Medicine
pubs.publication-status Published online
pubs.volume 9
dc.identifier.eissn 1476-511X

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