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dc.contributor.author Denslow, SA
dc.contributor.author Westreich, DJ
dc.contributor.author Firnhaber, C
dc.contributor.author Michelow, P
dc.contributor.author Williams, S
dc.contributor.author Smith, JS
dc.coverage.spatial Ireland
dc.date.accessioned 2012-10-23T19:40:00Z
dc.date.issued 2011-09
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/21683359
dc.identifier S0020-7292(11)00246-3
dc.identifier.citation Int J Gynaecol Obstet, 2011, 114 (3), pp. 273 - 277
dc.identifier.uri http://hdl.handle.net/10161/5915
dc.description.abstract OBJECTIVE: To assess the effect of bacterial vaginosis (BV) on the risk of high-grade squamous intraepithelial lesions (HSIL) among HIV-seropositive women. METHODS: A hospital-based prospective cohort study of HIV-seropositive women was conducted in Johannesburg, South Africa from January 2005 to September 2009. Multivariate log-binomial and Poisson regressions were used to estimate prevalence and rate ratios, respectively. RESULTS: Among 1954 HIV-seropositive women, the baseline prevalence of HSIL was 17%. BV prevalence was high (54%) and showed no association with prevalence of HSIL (adjusted prevalence ratio, 1.12; 95% confidence intervals (CI), 0.92-1.35) nor with cervical lesion progression at follow-up visit (n=503) (adjusted rate ratio: 1.00; 95% CI, 0.65-1.53). CONCLUSION: Among HIV-seropositive women, BV was not associated with an increased risk of HSIL or cervical lesion progression.
dc.format.extent 273 - 277
dc.language eng
dc.language.iso en_US en_US
dc.relation.ispartof Int J Gynaecol Obstet
dc.relation.isversionof 10.1016/j.ijgo.2011.03.011
dc.subject Adolescent
dc.subject Adult
dc.subject Aged
dc.subject Cervical Intraepithelial Neoplasia
dc.subject Female
dc.subject HIV Seropositivity
dc.subject Humans
dc.subject Middle Aged
dc.subject Prospective Studies
dc.subject Risk Factors
dc.subject Uterine Cervical Neoplasms
dc.subject Vaginosis, Bacterial
dc.subject Young Adult
dc.title Bacterial vaginosis as a risk factor for high-grade cervical lesions and cancer in HIV-seropositive women.
dc.type Journal Article
duke.description.endpage 277 en_US
duke.description.issue 3 en_US
duke.description.startpage 273 en_US
duke.description.volume 114 en_US
dc.relation.journal International Journal of Gynecology and Obstetrics en_US
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/21683359
pubs.issue 3
pubs.organisational-group /Duke
pubs.organisational-group /Duke/Faculty
pubs.publication-status Published
pubs.volume 114
dc.identifier.eissn 1879-3479

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