Samei, EhsanSaunders, Robert SBadea, Cristian TGhaghada, Ketan BHedlund, Laurence WQi, YiYuan, HongBentley, Rex CMukundan, Srinivasan2018-03-132018-03-132009https://hdl.handle.net/10161/16180A long circulating liposomal, nanoscale blood pool agent encapsulating traditional iodinated contrast agent (65 mg I/mL) was used for micro-computed tomography (CT) imaging of rats implanted with R3230AC mammary carcinoma. Three-dimensional vascular architecture of tumors was imaged at 100-micron isotropic resolution. The image data showed good qualitative correlation with pathologic findings. The approach holds promise for studying tumor angiogenesis and for evaluating anti-angiogenesis therapies.angiogenesisbreast cancerliposomemicro-CTmolecular imagingsmall animal imagingAnimalsCell Line, TumorContrast MediaFemaleIopamidolLiposomesMammary Neoplasms, AnimalMammographyNanoparticlesRadiographic Image EnhancementRatsRats, Inbred F344Tomography, X-Ray ComputedJournal article1178-2013