Liu, YMurphy, SKMurtha, APFuemmeler, BFSchildkraut, JHuang, ZOvercash, FKurtzberg, JJirtle, RIversen, ESForman, MRHoyo, C2022-03-232022-03-232012-071559-23081559-2308https://hdl.handle.net/10161/24661Depressed mood in pregnancy has been linked to low birth weight (LBW, 4,500 g) infants had 5.9% higher methylation at the PLAGL1 DMR compared with normal birth weight infants. Our findings confirm that severe maternal depressed mood in pregnancy is associated with LBW, and that MEG3 and IGF2 plasticity may play important roles.HumansPregnancy ComplicationsBirth WeightInsulin-Like Growth Factor IICell Cycle ProteinsTumor Suppressor ProteinsTranscription FactorsRNA, UntranslatedSequence Analysis, DNADepressionDNA MethylationGenomic ImprintingPregnancyAdolescentAdultInfant, NewbornFemaleMaleGenetic LociHigh-Throughput Nucleotide SequencingRNA, Long NoncodingJournal article2022-03-23